Gamma-aminobutyric acid (GABA) is a chemical that is made in the brain and also found in some foods. In the brain, GABA has anti-seizure and anti-anxiety effects. GABA works by blocking brain signals (neurotransmissions). There is interest in using GABA as a dietary supplement. But when taken by mouth, GABA may not be able to cross the blood-brain barrier. Therefore it is unknown if GABA supplements have effects on the brain. People use GABA for many different conditions, including stress, anxiety, depression, and high blood pressure.
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